Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 11, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Topography-guided laser refractive surgery.

Simon Holland1, David T C Lin, Johnson C H Tan

  • 1Pacific Laser Eye Centre, University of British Columbia, Vancouver, British Columbia, Canada.

Current Opinion in Ophthalmology
|May 18, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antibiotic resistance of Pseudomonas aeruginosa from ocular samples in Canada: a 25-year analysis.

The ocular surface·2025
Same author

Transepithelial phototherapeutic keratectomy for treatment-resistant recurrent corneal erosion syndrome.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2024
Same author

Radial keratotomy and cataract surgery: A quest for emmetropia.

Journal of cataract and refractive surgery·2023
Same author

New treatment algorithm for keratoconus and cataract: small-aperture IOL insertion with sequential topography-guided photorefractive keratectomy and simultaneous accelerated corneal crosslinking.

Journal of cataract and refractive surgery·2021
Same author

Ten-year safety follow-up and post-explant analysis of an anterior chamber phakic IOL.

Journal of cataract and refractive surgery·2020
Same author

Refractive Outcomes of Descemet Membrane Endothelial Keratoplasty Combined With Cataract Surgery in Fuchs Endothelial Dystrophy.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2020
Same journal

Laser vision correction (LASIK, PRK, SMILE) with simultaneous accelerated corneal crosslinking.

Current opinion in ophthalmology·2026
Same journal

Traumatic macular hole: observe, operate, or other options.

Current opinion in ophthalmology·2026
Same journal

The evolving role of artificial intelligence in ophthalmology: basic science, translation, and clinical integration.

Current opinion in ophthalmology·2026
Same journal

Editorial: reducing risk for refractive surgery.

Current opinion in ophthalmology·2026
Same journal

Updates on Refractive Surgery: Benefits, Risks, and Costs of Modern Treatment Options.

Current opinion in ophthalmology·2026
Same journal

Corneal Allogeneic Intrastromal Ring Segments for keratoconus - recent evidence and the move to customized and custom shaped CAIRS.

Current opinion in ophthalmology·2026
See all related articles

Topography-guided laser surgery effectively corrects irregular corneas, even in complex cases unsuitable for wavefront aberrometry. This advanced technique shows promise for improving vision and managing conditions like keratectasia.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Refractive Surgery

Background:

  • Corneal irregularities pose challenges for standard refractive surgery.
  • Wavefront aberrometry is limited in highly aberrated eyes.

Purpose of the Study:

  • Review recent outcomes of topography-guided ablations.
  • Evaluate applications in normal, irregular, and keratectasia corneas.
  • Assess combined topography-guided ablation with collagen cross-linking (CXL).

Main Methods:

  • Review of published literature on topography-guided laser ablations.
  • Analysis of outcomes in various corneal conditions.
  • Evaluation of combined CXL and ablation techniques.

Main Results:

More Related Videos

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

Related Experiment Videos

Last Updated: May 11, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

  • Topography-guided ablation demonstrates efficacy and safety in highly aberrated corneas.
  • Successful treatment of post-refractive surgery complications and irregular astigmatism.
  • Promising results for combined topography-guided ablation and CXL in keratectasia.

Conclusions:

  • Topography-guided laser surgery is effective for visual rehabilitation in highly aberrated eyes.
  • Predictability is improving with ongoing research.
  • Well-tolerated procedure with positive outcomes.