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Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
Actinobaculum schaalii causing epididymitis in an elderly patient
S van Aarle1, N L A Arents2, K de Laet1
1Department of Urology, Maxima Medical Center, Veldhoven, The Netherlands.
Journal of Medical Microbiology
|May 18, 2013
Summary
Actinobaculum schaalii, a Gram-positive bacterium, can cause infections. This study reports the first documented case of epididymitis, an inflammation of the coiled tube at the back of the testicle, caused by this often-overlooked pathogen.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Urology
Background:
- Actinobaculum schaalii is a Gram-positive coccoid rod implicated in human infections.
- Historically, A. schaalii was considered a low-prevalence pathogen with limited invasive potential, primarily causing cystitis in elderly patients with urological issues.
Observation:
- This report details a novel case of epididymitis.
- The infection was attributed to Actinobaculum schaalii.
Findings:
- The study presents the first documented instance of A. schaalii causing epididymitis.
- This finding expands the known spectrum of clinical manifestations associated with this bacterium.
Implications:
- The identification of A. schaalii as a cause of epididymitis highlights the need for increased awareness of this pathogen in genitourinary infections.
- Clinicians should consider A. schaalii in the differential diagnosis of epididymitis, particularly in patients with risk factors.
- Further research may be warranted to understand the pathogenesis and optimal treatment strategies for A. schaalii-associated epididymitis.
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