Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developing the PATH-GP (Prevention and Testing for HIV in General Practice) intervention: a person-based approach intervention development study to increase HIV testing and PrEP access.

The British journal of general practice : the journal of the Royal College of General Practitioners·2025
Same author

The Impact of a Planned Change to Nurse Staffing Levels in Emergency Departments: A Pre-Test, Post-Test Design.

Journal of advanced nursing·2025
Same author

De-escalating aggression in acute inpatient mental health settings: a behaviour change theory-informed, secondary qualitative analysis of staff and patient perspectives.

BMC psychiatry·2024
Same author

Facilitators and barriers to community pharmacy PrEP delivery: a scoping review.

Journal of the International AIDS Society·2024
Same author

The association between nurse staffing and quality of care in emergency departments: A systematic review.

International journal of nursing studies·2024
Same author

The person-based development and realist evaluation of a pre-consultation form for GP consultations.

NIHR open research·2023
Same journal

An Intentional and Ethical Integration of AI in Medical Imaging.

Radiologic technology·2026
Same journal

Benefits of Integrating AI Into Computer-Aided Detection Systems.

Radiologic technology·2026
Same journal

Using Artificial Intelligence to Enhance Analysis of Chest Computed Tomography.

Radiologic technology·2026
Same journal

A Practice-Aligned Approach to Integrating AI in Radiation Sciences Education.

Radiologic technology·2026
Same journal

Site Visitors: The Unsung Heroes of the Accreditation Process.

Radiologic technology·2026
Same journal

Extended Reality Innovations in Medical Imaging Education.

Radiologic technology·2026
See all related articles

Related Experiment Video

Updated: May 11, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Cystic fibrosis.

Anne Scott1

  • 1Sports Medicine Clinic, Duke University Medical Center in Durham, North Carolina, USA.

Radiologic Technology
|May 21, 2013
PubMed
Summary
This summary is machine-generated.

Cystic fibrosis (CF) is a genetic disorder impacting ion transport, leading to thick mucus in organs like the lungs. Medical imaging aids in monitoring CF

More Related Videos

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression
08:58

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression

Published on: April 18, 2025

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
08:00

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

Published on: April 11, 2018

Related Experiment Videos

Last Updated: May 11, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression
08:58

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression

Published on: April 18, 2025

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
08:00

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

Published on: April 11, 2018

Area of Science:

  • Genetics and Molecular Biology
  • Medical Imaging
  • Pulmonology

Background:

  • Cystic fibrosis (CF) is an autosomal recessive genetic disorder.
  • It disrupts ion transport in exocrine glands, causing dehydration and thick secretions.
  • CF affects multiple organs, including the lungs, pancreas, and digestive system.

Purpose of the Study:

  • To discuss the respiratory and nonrespiratory manifestations of cystic fibrosis.
  • To describe the diagnosis and treatment of cystic fibrosis.
  • To cover methods for minimizing radiation exposure in pediatric patients undergoing imaging.

Main Methods:

  • Review of current medical literature on cystic fibrosis.
  • Discussion of diagnostic methods, including sweat chloride testing.
  • Analysis of imaging techniques used to monitor CF-related pathology.

Main Results:

  • Cystic fibrosis leads to significant respiratory complications and affects various organ systems.
  • Medical imaging is crucial for assessing disease progression and treatment response.
  • Radiation dose reduction strategies are important for pediatric CF patients.

Conclusions:

  • Cystic fibrosis requires comprehensive management addressing its multi-systemic effects.
  • Imaging plays a vital role in the long-term care of individuals with CF.
  • Minimizing radiation exposure is a key consideration in pediatric imaging for CF.