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Updated: May 11, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Lymphangioma and lymphangiectasia].
A Legras1, P Mordant, F Le Pimpec-Barthes
1Service de chirurgie thoracique, université Paris 5, hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, 20, rue Leblanc, 75015 Paris, France.
Primary thoracic lymphatic diseases, including lymphangiomas and lymphangiectasias, are rare. Diagnosis and management depend on imaging features and complications, with surgery reserved for difficult cases or when medical treatment fails.
Area of Science:
- Thoracic medicine
- Vascular biology
- Diagnostic imaging
Context:
- Primary thoracic lymphatic diseases, such as lymphangiomas and lymphangiectasias, are uncommon and potentially underdiagnosed.
- These conditions affect the lymphatic vessels within the chest, impacting lung function and fluid balance.
Purpose:
- To review the characteristics, diagnostic approaches, and management strategies for primary thoracic lymphatic diseases.
- To differentiate between lymphangiomas and lymphangiectasias based on their etiology and presentation.
Summary:
- Lymphangiomas involve lymphatic vessel proliferation, often linked to embryologic issues in children or obstruction in adults. Lymphangiectasias are dilatations without proliferation, potentially leading to chylous effusions if connected to the thoracic duct.
- Computed tomography (CT) and magnetic resonance imaging (MRI) are crucial for diagnosis. Surgical resection is indicated for diagnostic uncertainty or complications, while medical management is the initial approach for uncomplicated cases.
- Lymphangio MRI aids in visualizing lymphangiectasias and the thoracic duct, guiding treatment decisions. Refractory cases may necessitate surgical intervention.
Impact:
- Improved understanding of rare thoracic lymphatic disorders.
- Guidance on diagnostic imaging interpretation and treatment selection.
- Highlights the importance of early diagnosis and appropriate management to prevent complications like chylothorax.
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