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Laryngeal sarcoidosis: a case report presenting transglottic involvement
Emke M J M van den Broek1, Bas J Heijnen, Berit M Verbist
1Department of Otorhinolaryngology/Head and Neck Surgery, Leiden University Medical Centre, Leiden, The Netherlands. E.M.J.M.van_den_Broek@lumc.nl
Summary
Isolated laryngeal sarcoidosis, a rare condition, presents uniquely with transglottic swelling. Systemic corticosteroids effectively treated this patient, highlighting a viable therapeutic option for this rare laryngeal disease.
Area of Science:
- Pulmonology
- Otorhinolaryngology
- Pathology
Background:
- Laryngeal sarcoidosis is an exceptionally rare manifestation of sarcoidosis.
- Typically, it presents as supraglottic swelling, but variations exist.
Observation:
- A patient presented with hoarseness and exertional dyspnea.
- Laryngeal examination revealed supraglottic edema, subglottic swelling, and edematous true vocal folds.
- Histological examination confirmed noncaseating granulomas.
Findings:
- The patient was diagnosed with isolated transglottic sarcoidosis after excluding other causes.
- Treatment with systemic corticosteroids resulted in a positive clinical outcome.
Implications:
- This case expands the understanding of laryngeal sarcoidosis presentation.
- It underscores the importance of considering sarcoidosis in unexplained laryngeal conditions.
- Systemic corticosteroids appear effective for managing isolated laryngeal sarcoidosis.
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