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[Branch retinal vein occlusion: high time for cardiovascular risk management]
1Universitair Medisch Centrum St Radboud, afd. Algemeen Interne Geneeskunde, Nijmegen, the Netherlands. s.bredie@aig.umcn.nl
Insights
Cardiovascular risk management is often overlooked in patients with branch retinal vein occlusion (BRVO). This common eye condition is a significant indicator of underlying cardiovascular disease, necessitating proactive risk management.
Area of Science:
- Ophthalmology
- Cardiology
- Vascular Medicine
Background:
- Cardiovascular risk management is standard for patients with established cardiovascular disease, hypertension, hyperlipidemia, and diabetes mellitus.
- Branch retinal vein occlusion (BRVO) is a prevalent retinal vascular disorder, particularly in middle-aged and elderly individuals.
- Despite its association with cardiovascular risk factors, cardiovascular risk management is infrequently implemented for BRVO patients.
Purpose of the Study:
- To highlight the underutilization of cardiovascular risk management in patients diagnosed with branch retinal vein occlusion.
- To emphasize that BRVO serves as an important marker for identifying individuals at elevated risk of future cardiovascular events.
- To advocate for the integration of comprehensive cardiovascular risk assessment and management in the care of BRVO patients.
Main Methods:
- Review of existing literature on branch retinal vein occlusion and its association with systemic vascular diseases.
- Analysis of the etiological factors contributing to BRVO, distinguishing between thrombotic and non-thrombotic causes.
- Examination of longitudinal studies correlating BRVO with the subsequent development of cardiovascular and cerebrovascular diseases.
Main Results:
- Branch retinal vein occlusion is frequently linked to pre-existing conditions such as diabetes, hypertension, and peripheral artery disease.
- Individuals with BRVO demonstrate a significantly increased risk of developing hypertension, diabetes, congestive heart failure, and cerebrovascular disease.
- The pathophysiology of BRVO involves arterial compression of the retinal vein, with procoagulant disorders being relevant only in specific cases.
Conclusions:
- Branch retinal vein occlusion is a critical indicator of generalized cardiovascular disease and should prompt thorough cardiovascular risk assessment.
- Adequate cardiovascular risk management, similar to that for patients with manifest cardiovascular disease, is warranted for individuals with BRVO.
- Early and consistent management of cardiovascular risk factors in BRVO patients may help mitigate future cardiovascular and cerebrovascular complications.
Abstract:
Cardiovascular risk management is common in patients suffering from manifest cardiovascular disease, hypertension, hyperlipidaemia and diabetes mellitus. It is generally accepted that medication is the most effective treatment for reducing cardiovascular morbidity and mortality in these patients. Remarkably, cardiovascular risk management is rare in patients suffering from branch retinal vein occlusion. This common retinal vascular disorder in middle aged and elderly people occurs where a thickened retinal artery compresses the affected vein. Although thrombosis is involved, procoagulant disorders are only present in selected cases. On the other hand, prior diabetes, hypertension, and peripheral artery disease are associated with an increased risk of developing branch retinal vein occlusion up to a decade later, and retinal vascular disorder is associated with an increased risk of subsequently developing hypertension, diabetes, congestive heart failure, and cerebrovascular disease later on. Therefore, branch retinal vein occlusion is a marker of developing cardiovascular disease and warrants adequate cardiovascular risk management.
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