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Updated: May 11, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
Published on: December 20, 2024
Non-traumatic splenic rupture in a patient on oral anticoagulation
Marije M de Kubber1, Lucia Jm Kroft, Bas de Groot
1Department of Emergency Medicine, Leiden University Medical Centre, Albinusdreef 2, 2333 Leiden, ZA, the Netherlands. m.m.de_kubber@lumc.nl.
Background:
Splenic injury is normally associated with trauma, but spontaneous splenic rupture has been described in various systemic diseases.
Case Presentation:
A 56-year-old male on oral anticoagulation presented to the emergency department with epigastric pain, nausea, and left upper quadrant tenderness. There was no history of trauma. Contrast-enhanced CT imaging revealed a large subcapsular haematoma of the spleen. Oral anticoagulation was antagonised with vitamin K and the patient was discharged in good condition after 3 days of clinical observation.
Conclusion:
Non-traumatic splenic rupture is a rare complication of oral anticoagulation.
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