Related Experiment Videos
Chronic recurrent multifocal osteomyelitis
Patrícia Costa-Reis1, Kathleen E Sullivan
1The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. pcr.patricia@gmail.com
Abstract:
Chronic recurrent multifocal osteomyelitis is a rare auto-inflammatory condition that primarily affects children and adolescents. It presents with recurrent episodes of pain related to the presence of foci of sterile bone inflammation. The long bones of the lower extremities are more frequently affected and the spine can also be involved. Imaging studies, including whole-body magnetic resonance, are important for diagnosis and detection of asymptomatic lesions. Bone biopsies may be necessary to exclude other diseases, including malignancy and infections. Non-steroidal anti-inflammatory drugs cause relief of symptoms in the majority of cases. Bisphosphonates and TNF-α blockers are alternatives for patients who do not respond or who have spinal involvement.
Related Concept Videos
Atypical Pneumonia
Acute Pyelonephritis II: Diagnostic Studies and Management
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Cardiomyopathy IV: Restrictive Cardiomyopathy
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations