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Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia
Michele M Squire1, Glen P Carter, Kate E Mackin
1The University of Western Australia, Nedlands, Western Australia, Australia.
Emerging Infectious Diseases
|May 24, 2013
Abstract:
Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.
