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Characteristics of headache in children with epilepsy
Hideaki Kanemura1, Fumikazu Sano, Sayaka Ishii
1Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Japan. ykimu@yamanashi.ac.jp
Insights
Headache is common in children with epilepsy, particularly those with partial seizures and more frequent seizure attacks. Frontal headaches were most reported, though not always linked to the seizure
Area of Science:
- Neurology
- Pediatric Epilepsy
- Headache Disorders
Background:
- Headache associated with seizures is a recognized but poorly understood phenomenon.
- Epilepsy affects children and adults, with varying seizure types and presentations.
Purpose of the Study:
- To investigate the prevalence and characteristics of seizure-associated headaches in pediatric epilepsy patients.
- To identify risk factors for these headaches, focusing on seizure classification and epileptogenic focus.
Main Methods:
- Prospective study involving 98 pediatric epilepsy patients (ages 5-18) on active treatment.
- Patients were interviewed via questionnaire regarding seizure-associated headaches.
Main Results:
- 34.7% of patients reported seizure-associated headaches.
- Headaches were significantly more frequent in partial seizures (41.9%) than generalized seizures (12.5%).
- Patients with seizure-associated headaches experienced more frequent seizures (4.1/year vs. 1.3/year).
Conclusions:
- Headache is more common in pediatric partial epilepsy and with frequent seizures.
- Headache location did not consistently correlate with electroencephalographic focus.
- Findings highlight the need for further understanding of seizure-headache links in epilepsy.
Purpose:
The association of headache with seizures is well known to neurologists but poorly understood. The purpose of this prospective study was to evaluate the types and frequency of seizure-associated headaches among pediatric patients with epilepsy, and to identify their risk factors with special attention to the anatomic localization of the epileptogenic focus and seizure classification.
Methods:
Patients with focal and generalized active seizures and on treatment at the time of questionnaire administration were included. Patients were prospectively interviewed by questionnaire as to whether or not they suffered from headaches associated with epileptic seizures.
Results:
Of 98 patients (age range: 5-18 years), 34 (34.7%) complained of seizure-associated headaches. In patients with seizure-associated headaches, headache was significantly more frequent (31/74, 41.9%) with partial seizures than with generalized seizures (3/24, 12.5%; p=0.012). The frequency of seizure attacks was 4.1 times per year in patients with seizure-associated headache and 1.3 times per year in those with non-seizure-associated headache. Of the 34 patients, 20 (58.8%) complained of headache at the frontal region.
Conclusions:
The location of headache was not always in agreement with electroencephalographic focus. Headache was more frequent in patients with partial epilepsy and frequent seizures.
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