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Intravenous infusions in chronic pain management
Boleslav Kosharskyy1, Wilson Almonte, Naum Shaparin
1Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA. bkoshars@montefiore.org
Pain Physician
|May 25, 2013
Summary
Non-opiate intravenous infusions offer potential relief for chronic pain conditions like fibromyalgia and neuropathic pain. This review explores lidocaine, ketamine, and other infusions, highlighting their use in pain management.
Area of Science:
- Pain Management
- Pharmacology
- Neurology
Background:
- Chronic pain affects millions in the US, increasing morbidity, mortality, and disability.
- The economic burden of chronic pain is substantial, estimated at $560-635 billion annually.
- Intravenous infusions are explored for significant pain relief in chronic conditions.
Purpose of the Study:
- To review non-opiate intravenous infusions for chronic painful disorders.
- To familiarize practitioners with various infusion options for chronic pain.
- To discuss infusions for conditions including fibromyalgia, neuropathic pain, and CRPS.
Main Methods:
- Literature review of non-opiate intravenous infusions.
- Focus on agents like lidocaine, ketamine, phentolamine, dexmedetomidine, and bisphosphonates.
- Analysis of their utilization in chronic pain management.
Main Results:
- Certain infusions are well-established, while others require further investigation.
- The reviewed infusions have been used for conditions such as fibromyalgia, neuropathic pain, and CRPS.
- Evidence for specific guidelines on their use is currently limited.
Conclusions:
- Non-opiate IV infusions represent a diverse therapeutic avenue for chronic pain.
- Continued research is needed to establish definitive guidelines for their application.
- These infusions offer alternatives for patients with challenging chronic pain conditions.
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