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Colpocephaly in adults

Charles C Esenwa1, David E Leaf

  • 1Department of Neurology, Columbia University Medical Center, New York, New York, USA. cce2117@columbia.edu

BMJ Case Reports
|May 25, 2013
PubMed

Insights

Colpocephaly, a brain abnormality, is typically diagnosed in infants but can occur in adults. This case highlights the need to consider colpocephaly in adults with specific brain ventricle enlargement.

Area of Science:

  • Neurology
  • Radiology
  • Developmental Biology

Background:

  • Colpocephaly is a congenital brain abnormality affecting the ventricular system.
  • Radiological diagnosis is common in the perinatal period and often linked to intellectual disability.

Observation:

  • A rare case of massive colpocephaly diagnosed in an adult woman is presented.
  • The patient is otherwise a functional individual, challenging typical presentations.

Findings:

  • Colpocephaly involves disproportionate ventriculomegaly, particularly affecting the occipital horns.
  • This condition must be differentiated from idiopathic normal pressure hydrocephalus (NPH) in adults.

Implications:

  • The study broadens the understanding of colpocephaly's potential presentation in adulthood.
  • It emphasizes the importance of considering colpocephaly in adult ventriculomegaly diagnoses.
  • Accurate differentiation from NPH is crucial for appropriate patient management.

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