Related Experiment Video
Updated: May 11, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Videofluoroscopic swallowing study findings in full-term and preterm infants with Dysphagia
Kyeong Eun Uhm1, Sook-Hee Yi, Hyun Jung Chang
1Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Insights
This study reveals distinct clinical features and swallowing difficulties in full-term versus preterm infants with dysphagia. Understanding these differences aids in diagnosing and managing infant feeding disorders.
Area of Science:
- Pediatrics
- Neonatology
- Speech-Language Pathology
Background:
- Infant dysphagia presents unique challenges in clinical assessment and diagnostic evaluation.
- Differentiating between full-term and preterm infants is crucial due to potential variations in pathophysiology and presentation.
- Videofluoroscopic swallowing studies (VFSS) are a key diagnostic tool for evaluating swallowing function.
Purpose of the Study:
- To characterize clinical presentations and VFSS findings in infants with suspected dysphagia.
- To compare these characteristics and findings between full-term and preterm infant populations.
- To identify potential differences in the underlying mechanisms of dysphagia.
Main Methods:
- Retrospective analysis of 107 infants (67 full-term, 40 preterm) referred for VFSS.
- Review of clinical data and VFSS results by a physiatrist and speech-language pathologist.
- Analysis of associations between referral reasons and VFSS outcomes.
Main Results:
- Common referral reasons included poor sucking (full-term) and desaturation (preterm).
- Congenital heart disease (full-term) and bronchopulmonary dysplasia (preterm) were frequent comorbidities.
- Aspiration occurred in 39.3% of infants, with silent aspiration in 81%. Coughing was the sole clinical predictor of aspiration.
- No significant VFSS differences were found between groups, except for decreased sustained sucking in preterm infants.
Conclusions:
- Clinical and VFSS findings in infants with dysphagia show variations between full-term and preterm infants.
- These differences highlight distinct pathophysiologic mechanisms contributing to dysphagia in each group.
- The study enhances understanding for targeted diagnosis and management of infant feeding disorders.
Objective:
To determine the clinical characteristics and videofluoroscopic swallowing study (VFSS) findings in infants with suspected dysphagia and compare the clinical characteristics and VFSS findings between full-term and preterm infants.
Methods:
A total of 107 infants (67 full-term and 40 preterm) with suspected dysphagia who were referred for VFSS at a tertiary university hospital were enrolled in this retrospective study. Clinical characteristics and VFSS findings were reviewed by a physiatrist and an experienced speech-language pathologist. The association between the reasons of referral for VFSS and VFSS findings were analyzed.
Results:
Mean gestational age was 35.1±5.3 weeks, and mean birth weight was 2,381±1,026 g. The most common reason for VFSS referral was 'poor sucking' in full-term infants and 'desaturation' in preterm infants. The most common associated medical condition was 'congenital heart disease' in full-term infants and 'bronchopulmonary dysplasia' in preterm infants. Aspiration was observed in 42 infants (39.3%) and coughing was the only clinical predictor of aspiration in VFSS. However, 34 of 42 infants (81.0%) who showed aspiration exhibited silent aspiration during VFSS. There were no significant differences in the VFSS findings between the full-term and preterm infants except for 'decreased sustained sucking.'
Conclusion:
There are some differences in the clinical manifestations and VFSS findings between full-term and preterm infants with suspected dysphagia. The present findings provide a better understanding of these differences and can help clarify the different pathophysiologic mechanisms of dysphagia in infants.
Related Concept Videos
Upper GI Series: Barium Swallow
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Deglutition
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
Pyloric Obstruction
