Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbes and Other Elemental Cycles01:24

Microbes and Other Elemental Cycles

Microbial activity plays a pivotal role in the biogeochemical cycling of iron and manganese, especially at the redox gradients characteristic of stratified aquatic environments. These cycles are driven by microbial transformations between oxidized and reduced forms of the metals, allowing organisms to exploit them for metabolic energy and structural purposes.Iron Cycling Across Redox GradientsIn neutral, oxygen-rich surface waters, iron is predominantly found in its oxidized, insoluble ferric...
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

OverviewElements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information...
Balancing Redox Equations02:58

Balancing Redox Equations

Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
The Early Endosome: Endocytosis of Transferrin01:28

The Early Endosome: Endocytosis of Transferrin

Essential proteins such as insulin or low-density lipoprotein (LDL) and micronutrients such as iron enter a eukaryotic cell through receptor-mediated endocytosis. Subsequently, the early endosomes fuse with the vesicles containing such receptor-ligand complexes and play a vital role in sorting the incoming ligands and receptors. While the ligands are either degraded inside the vesicle or released into the cytosol, their receptors are returned to the plasma membrane for further rounds of...
Corrosion02:49

Corrosion

The degradation of metals due to natural electrochemical processes is known as corrosion. Rust formation on iron, tarnishing of silver, and the blue-green patina that develops on copper are examples of corrosion. Corrosion involves the oxidation of metals. Sometimes it is protective, such as the oxidation of copper or aluminum, wherein a protective layer of metal oxide or its derivatives forms on the surface, protecting the underlying metal from further oxidation. In other cases, corrosion is...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of student confidence, knowledge, and attitudes after use of interactive computer modules in a university-level cardiovascular physiology course.

Advances in physiology education·2026
Same author

Two artificial intelligence models underperform on examinations in a veterinary curriculum.

Journal of the American Veterinary Medical Association·2024
Same author

Impact of apitherapy on canine, equine, and chicken lymphocytes, in vitro.

Veterinary immunology and immunopathology·2024
Same author

Validation of a commercially available photometric analytical system for assessment of plasma oxidative status in healthy horses.

Veterinary immunology and immunopathology·2023
Same author

A Randomized, Self-Controlled Case Series Evaluating Core Osteostixis of Osseous Cyst-Like Lesions of the Navicular Bone to Improve Lameness in Horses with Podotrochlear Syndrome.

Veterinary medicine (Auckland, N.Z.)·2023
Same author

Hematologic profiles and development of innate immune function in healthy Holstein calves during the pre-weaning period.

Veterinary clinical pathology·2022
Same journal

Clinical snapshot: Dripping fluid from the prepuce of a paint horse.

Compendium (Yardley, PA)·2013
Same journal

Feline focus: Diagnostic testing for feline thyroid disease: hypothyroidism.

Compendium (Yardley, PA)·2013
Same journal

Feline focus: Diagnostic testing for feline thyroid disease: hyperthyroidism.

Compendium (Yardley, PA)·2013
Same journal

Heatstroke: clinical signs, diagnosis, treatment, and prognosis.

Compendium (Yardley, PA)·2013
Same journal

Clinical snapshot: equine lymphoma.

Compendium (Yardley, PA)·2013
Same journal

Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis.

Compendium (Yardley, PA)·2013
See all related articles

Related Experiment Video

Updated: May 11, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Iron and exercise: a ferric balancing act.

David J Hurley1, James N Moore

  • 1djhurley@uga.edu

Compendium (Yardley, PA)
|May 28, 2013
PubMed
Summary
This summary is machine-generated.

Iron deficiency impacts global health, affecting immune, neural, and metabolic systems. This review examines the fundamental biology of iron, highlighting knowledge gaps in its role in health and disease.

More Related Videos

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
04:48

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))

Published on: May 4, 2020

A Colorimetric Method for Measuring Iron Content in Plants
07:12

A Colorimetric Method for Measuring Iron Content in Plants

Published on: September 7, 2018

Related Experiment Videos

Last Updated: May 11, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
04:48

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))

Published on: May 4, 2020

A Colorimetric Method for Measuring Iron Content in Plants
07:12

A Colorimetric Method for Measuring Iron Content in Plants

Published on: September 7, 2018

Area of Science:

  • Nutritional Science
  • Human Physiology
  • Biochemistry

Background:

  • Iron deficiency is a global health concern with estimated widespread negative consequences.
  • The Belmont Conference critically re-evaluates iron status in relation to physiological, biochemical, and neurological outcomes.
  • Iron's dual role as an essential nutrient and a cellular toxicant necessitates complex regulatory mechanisms.

Purpose of the Study:

  • To reconsider the established links between iron status and various health outcomes.
  • To focus on the biological underpinnings of how iron status affects the immune system, neural function, and energy metabolism.
  • To identify significant gaps in the understanding of iron biology and its dependent processes.

Main Methods:

  • Literature review focusing on the biological processes affected by iron status.
  • Assessment of the strength of evidence across domains including immune function, neural systems, and energy metabolism.
  • Identification of knowledge gaps in basic iron biology.

Main Results:

  • Evidence suggests alterations in the immune system, neural systems, and energy metabolism are linked to iron status.
  • Significant gaps in fundamental biological knowledge regarding iron-dependent processes were identified.
  • Iron's complex regulation is crucial for cellular function and preventing toxicity.

Conclusions:

  • A deeper understanding of iron's basic biology is essential for addressing its impact on health.
  • Further research is needed to fully elucidate the relationship between iron status and morbidity, mortality, and population health.
  • This review sets the foundation for future investigations into the clinical implications of iron deficiency.