Related Experiment Video
Updated: May 2, 2026
Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
[Anticancer activity of Crocodylus siamensis blood in vitro and in vivo]
Di Geng1, Yu-Long Duan, Xiao-Lin Xu
1Department of Biological Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. piece124@hotmail.com
Objective:
To study the anticancer effects of the blood of Crocodylus siamensis in vitro and in vivo.
Methods:
The inhibitory effects of serum and plasma of Crocodylus siamensis on proliferation of HepG2, BGC823, HeLa and SKOV3 cell were measured by MTT assay. The mouse S180 tumor model was used to evaluate the anti-tumor effect in vivo.
Results:
High dosage serum and plasma of Crocodylus siamensis could inhibit the proliferation of HepG2, BGC823, HeLa and SKOV3 cell. The tumor inhibitory rate of high dosage blood of Crocodylus siamensis on S180 tumor was up to 57.55%.
Conclusion:
The blood of breeding Crocodylus siamensis has anticancer activity.
