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[Spectrum-effect relationship in effect of improving immunity of astragali radix]
Xiao-Hua Liu1, Jin Liang, Yuan Ren
1liuxiaoh@Lzu.edu.cn
Objective:
To elaborate the correlation of chromatography fingerprint of Astragali Radix and the efficacy of improving immunity, and express the effective substances foundation.
Methods:
The water extract was given to irrigation stomach of mice for carbon clearance experiment. Associated the peak area of each common peak from HPLC fingerprint and the date of improving immunity, and studied the correlation between fingerprint and efficacy and found out the effective substances foundation of improving immunity in the method of gray correlation analysis.
Results:
Polysacharides was the main component of the water extract of Astragali Radix, which could improve immunity function. In carbon clearance experiment, the phagocytic index of the mice with water extract was the largest, and the ability to enhance immunity was the strongest. Grey correlation analysis was used to evaluate the correlation of the effect of improving immunity and the component of the water extract of Astragali Radix.
Conclusion:
It is effective to study the fingerprint and the correlation of fingerprint and the efficacy of traditional chinese medicine for expressing its correlation.
