Different types of physical activity on inflammatory biomarkers in women with or without metabolic disorders: a...

Overwhelming data support the relationship between physical inactivity and inflammatory processes underlying metabolic disorders. The aim of this review was to assess critically the body of evidence for the relationships between exercise protocols and levels of inflammatory biomarkers in women. Systematic literature searches using PubMed Medline, Cochrane Central Register of Controlled Trials, Web of Science, LILACS, and SciELO of publications from 1993 to January 2012 were conducted using the following keywords: inflammation, cytokine, exercise, physical training, aerobic training, cardiovascular training, strength training, resistance training, interval training, cardiac rehabilitation, and therapeutic lifestyle modification/management. Three studies reported no significant changes in inflammatory status, one documented an increase in inflammatory biomarkers, and 12 articles reported decreased inflammatory biomarkers associated with exercise. Secondary lifestyle characteristics, such as strenuous physical labor or smoking, were correlated with levels of inflammatory biomarkers. Integrative interventions, including diet, moderate aerobic (60% to 80% of maximum heart rate, or 50% to 60% of VO2max) and circuit resistance training (8 to 10 exercises, 8 to 12 repetitions), health education, and counseling, used together, appeared to be effective strategies to improve inflammatory biomarkers in women.