Induced protein polymorphisms and nutritional quality of gamma irradiation mutants of sorghum
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Updated: May 11, 2026

Identifying Mutations by High Resolution Melting in a TILLING Population of Rice
Published on: September 2, 2019
Luke Mehlo1, Zodwa Mbambo, Souleymane Bado
1CSIR Biosciences, Meiring Naude Road, P.O. Box 395, Pretoria 0001, South Africa.
Abstract:
Physical and biochemical analysis of protein polymorphisms in seed storage proteins of a mutant population of sorghum revealed a mutant with redirected accumulation of kafirin proteins in the germ. The change in storage proteins was accompanied by an unusually high level accumulation of free lysine and other essential amino acids in the endosperm. This mutant further displayed a significant suppression in the synthesis and accumulation of the 27kDa γ-, 24kDa α-A1 and the 22kDa α-A2 kafirins in the endosperm. The suppression of kafirins was counteracted by an upsurge in the synthesis and accumulation of albumins, globulins and other proteins. The data collectively suggest that sorghum has huge genetic potential for nutritional biofortification and that induced mutations can be used as an effective tool in achieving premium nutrition in staple cereals.
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