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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

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Juvenile cellular pleomorphic adenoma.

Anuradha Ananthaneni¹, Suresh Babu Undavalli

¹Department of Oral Pathology, St Joseph Dental College, Eluru, Andhra Pradesh, India. anuradhaundavalli@yahoo.com

BMJ Case Reports

|May 28, 2013

Summary

This summary is machine-generated.

This study reports a rare case of juvenile pleomorphic adenoma in a 12-year-old girl, highlighting its unusual cheek location and predominant epithelial component. The findings contribute to understanding rare pediatric salivary gland tumors.

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Area of Science:

Pediatric Oncology
Oral Pathology
Tumor Biology

Background:

Salivary gland tumors are rare in children, typically affecting major glands.
Intraoral pleomorphic adenoma, especially in the cheek, is uncommon in pediatric patients.
Pleomorphic adenomas exhibit diverse histology due to epithelial and mesenchymal components from a single cell clone.

Observation:

A rare case of juvenile pleomorphic adenoma occurred in the cheek mucosa of a 12-year-old girl.
Histological examination revealed a predominant epithelial component.
This presentation is unusual given the rarity of minor salivary gland tumors in children and cheek involvement in adults.

Findings:

The juvenile pleomorphic adenoma in this case displayed a predominantly epithelial morphology.
Cytological and cytogenetic aspects were analyzed in the context of relevant literature.
The tumor originated from a single cell clone, characteristic of pleomorphic adenomas.

Implications:

This case expands the understanding of rare pediatric salivary gland neoplasms.
It underscores the importance of considering pleomorphic adenoma in the differential diagnosis of pediatric cheek masses.
Further research into the cytogenetics of pediatric pleomorphic adenomas may reveal specific diagnostic or therapeutic targets.