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Updated: May 11, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Alcoholism and its effects on the central nervous system
1Department of Biochemistry, VCSG Government Institute of Medical Science & Research, Srinagar, Pauri Garhwal, Uttaranchal-246174, India. sukhes.mukherjee@gmail.com
Alcohol abuse significantly impacts the central nervous system (CNS), causing brain damage and cognitive deficits. Understanding these effects is crucial for public health and treatment strategies.
Area of Science:
- Neuroscience
- Toxicology
- Public Health
Background:
- Alcohol abuse is a global health issue with substantial economic costs.
- Alcohol readily crosses biological barriers, affecting various body tissues, including the brain.
- Chronic excessive alcohol consumption leads to cognitive and memory impairments.
Purpose of the Study:
- To review the impact of alcoholism on the central nervous system (CNS).
- To highlight the mechanisms through which alcohol affects brain function and structure.
- To discuss the implications for human health.
Main Methods:
- Literature review of studies on alcohol's neurological effects.
- Analysis of research on neuro-cognitive deficits in alcoholics.
- Examination of direct and indirect mechanisms of alcohol-induced brain injury.
Main Results:
- Alcohol causes brain tissue contraction, neuronal damage, and central nervous system depression.
- It interferes with neurotransmission by interacting with brain receptors.
- Neuro-cognitive deficits, neuronal injury, and neurodegeneration are documented consequences.
Conclusions:
- Alcoholism has profound detrimental effects on the CNS.
- The precise mechanisms underlying alcohol-induced neurodegeneration require further elucidation.
- Addressing alcoholism is critical for mitigating its widespread impact on human health.
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