Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Primary study on origination of bone marrow abnormal clones in patients with myelodysplastic syndrome].

Zhongguo shi yan xue ye xue za zhi·2011

Same author

Clinical management of gastric cancer: results of a multicentre survey.

BMC cancer·2011

Same author

[Surveys on resources and varieties on Chinese markets of crude drug mahuang].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2011

Same author

Synthesis of 1,5-benzothiazepine derivatives bearing 2-phenoxy-quinoline moiety via 1,3-diplolar cycloaddition reaction.

Molecular diversity·2011

Same author

Three-dimensional magnetic assembly of microscale hydrogels.

Advanced materials (Deerfield Beach, Fla.)·2011

Same author

The assembly of cell-encapsulating microscale hydrogels using acoustic waves.

Biomaterials·2011

Search research articles

Related Experiment Video

Updated: May 11, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Directed self-assembly of microscale hydrogels by electrostatic interaction.

Yu Long Han¹, Yanshen Yang, Shaobao Liu

¹The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University School of Life Science and Technology, Xi'an 710049, People's Republic of China.

|May 30, 2013

Summary

This summary is machine-generated.

Electrostatic self-assembly of charged microgels, using poly(ethylene glycol) (PEG), creates complex biological structures. This novel bottom-up approach offers precise control for applications in tissue engineering and drug delivery.

More Related Videos

Preparation of Mechanically Stable Self-Assembled Peptides Hydrogels

Preparation of Mechanically Stable Self-Assembled Peptides Hydrogels

Published on: September 6, 2024

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Related Experiment Videos

Last Updated: May 11, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Preparation of Mechanically Stable Self-Assembled Peptides Hydrogels

Preparation of Mechanically Stable Self-Assembled Peptides Hydrogels

Published on: September 6, 2024

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Area of Science:

Materials Science
Biotechnology
Nanotechnology

Background:

Microscale component assembly is crucial for advanced material fabrication.
Controlled self-assembly methods are needed for complex biological structures.
Electrostatic interactions offer a promising route for directed assembly.

Purpose of the Study:

To demonstrate the unique benefits of electrostatic self-assembly for microscale components in solution.
To develop a novel bottom-up assembly approach using oppositely charged microgels.
To investigate the fundamental principles governing electrostatic microgel interactions and pattern formation.

Main Methods:

Utilizing positive and negative treatments of poly(ethylene glycol) (PEG) microgels.
Employing electrostatic interactions between oppositely charged microgels for self-assembly.
Investigating the impact of microgel contact area on construct energy and final patterns.
Designing microgels to control layer thickness and number for multi-layer structures.

Main Results:

Demonstrated the first-time use of electrostatic self-assembly for microscale components in solution.
Successfully fabricated large, complex, multi-layer biological structures with accurate control.
Established that microgel contact area dictates the total energy and resultant patterns.
Showcased the ability to precisely control layer thickness and microgel count.

Conclusions:

Electrostatic self-assembly of charged microgels provides a powerful and controllable fabrication method.
The approach enables the creation of intricate, biologically relevant structures for advanced applications.
Findings support the potential of this technique in tissue engineering, regenerative medicine, and drug delivery.