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A generic strategy for pharmacological caging of growth factors for tissue engineering
Maria Karlsson1, Philipp S Lienemann, Natallia Sprossmann
1Faculty of Biology, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany.
Chemical Communications (Cambridge, England)
|May 30, 2013
Abstract:
The caging of small molecules has revolutionized biological research by providing a means to regulate a wide range of processes. Here we report on a generic pharmacological method to cage proteins in a similar fashion. The present approach is of value in both fundamental and applied research, e.g. in tissue engineering.
