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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...

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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Simply eczema.

Choon How How1, Joanne Hui Min Quah, Mark Jean Aan Koh

  • 1SingHealth Polyclinics - Sengkang, Sengkang Community Hub, Singapore 545025. how.choon.how@singhealth.com.sg

Singapore Medical Journal
|May 30, 2013
PubMed
Summary
This summary is machine-generated.

This article presents a structured approach for managing atopic eczema, emphasizing planned reviews, patient empowerment, and trigger avoidance for chronic skin condition care.

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Area of Science:

  • Dermatology
  • Primary Care Medicine
  • Chronic Disease Management

Background:

  • Atopic eczema is a prevalent chronic skin condition frequently managed in primary care settings.
  • Effective management requires addressing the condition's inherent chronic and atopic characteristics.

Purpose of the Study:

  • To outline a holistic and structured management strategy for atopic eczema in primary care.
  • To highlight key components for successful long-term care and acute flare management.

Main Methods:

  • Implementation of planned, regular reviews for atopic eczema patients.
  • Focus on patient empowerment through education and active participation in care.
  • Development of written action plans for both chronic and acute flare management.
  • Emphasis on identifying and avoiding specific environmental or lifestyle triggers.

Main Results:

  • A structured approach integrates planned reviews, patient empowerment, action plans, and trigger avoidance.
  • Identifies common management pitfalls, including inadequate emphasis on reviews and patient engagement.
  • Underscores the importance of addressing epidermal barrier repair during acute flares.

Conclusions:

  • A holistic, structured approach is essential for effective atopic eczema management in primary care.
  • Prioritizing patient empowerment and consistent follow-up improves chronic skin condition outcomes.
  • Addressing epidermal barrier dysfunction during flares is critical for comprehensive care.