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Related Concept Videos

Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

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Related Experiment Video

Updated: May 11, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Surgery for brain metastases.

Kurt Andrew Yaeger1, M Nathan Nair

  • 1Department of Neurosurgery, Georgetown University School of Medicine, Washington DC 20007, USA.

Surgical Neurology International
|May 30, 2013
PubMed
Summary
This summary is machine-generated.

Surgery can be a crucial treatment for brain metastases, especially for single lesions in controlled cancers, offering prolonged survival. It

Keywords:
Brain metastasessurvivaltreatment

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Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
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Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

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Last Updated: May 11, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
06:44

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Published on: June 7, 2020

Area of Science:

  • Neurosurgery
  • Oncology
  • Radiation Oncology

Background:

  • The role of surgery in treating brain metastases remains a subject of debate.
  • Patient selection is critical, as specific clinical factors influence outcomes.
  • Established treatment protocols often involve radiation therapy or stereotactic radiosurgery.

Purpose of the Study:

  • To evaluate the efficacy of surgical resection in managing brain metastases.
  • To determine the optimal role of surgery in conjunction with other treatment modalities.
  • To identify patient subgroups who benefit most from surgical intervention.

Main Methods:

  • Review of clinical characteristics and prognostic factors for patients with brain metastases.
  • Comparison of survival outcomes between surgical resection and radiation therapy.
  • Assessment of stereotactic radiosurgery (SRS) as a standalone or adjuvant therapy.

Main Results:

  • Surgical resection can lead to prolonged survival in select patients, particularly those with single metastatic lesions and well-controlled systemic disease.
  • Stereotactic radiosurgery (SRS) offers comparable survival benefits when used alone.
  • Adjuvant SRS following surgery further extends patient survival times.

Conclusions:

  • Surgery is a highly indicated treatment for specific cases of brain metastases, including single lesions in controlled systemic cancers.
  • Surgery remains essential for managing neurological emergencies requiring immediate tumor debulking.
  • A comprehensive clinical assessment is vital for tailoring treatment strategies, including surgery, for brain metastases.