Related Experiment Video
Updated: May 6, 2026

05:50
A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
Published on: August 7, 2018
12.0K
Radiologic and Patient-derived Predictors for Recurrent Lumbar Disc Herniation After Minimally Invasive Tubular
Paul C Emerson1, Samuel H Wakelin1, David Y Zhao2
1Georgetown University School of Medicine, Washington, District of Columbia, USA.
World Neurosurgery
|June 21, 2025
Summary
Recurrent lumbar disc herniation (rLDH) after minimally invasive discectomy occurs in 12.13% of cases. Modic endplate changes and subligamentous herniations are associated with increased rLDH risk, necessitating further research into predictive factors.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Surgery
Background:
- Lumbar discectomy is a common treatment for radiculopathy caused by lumbar disc herniation (LDH).
- Recurrent LDH (rLDH) after initial surgery can lead to persistent symptoms and the need for reoperation.
- Reoperation for rLDH is associated with poorer patient outcomes.
Purpose of the Study:
- To identify risk factors associated with recurrent lumbar disc herniation (rLDH) after minimally invasive discectomy.
- To compare the recurrence rates of minimally invasive discectomy with traditional open microdiscectomy.
- To analyze the association between specific herniation subtypes and Modic endplate changes with rLDH.
Main Methods:
- Retrospective review of a prospectively collected database of 404 patients undergoing minimally invasive discectomy for LDH (2013-2020).
- Assessment of patient-derived factors (age, BMI, smoking, diabetes) and radiologic factors (disc height, Modic changes, herniation subtype).
- Herniation subtypes classified as protrusion, subligamentous extrusion, transligamentous extrusion, or sequestration; statistical analysis of recurrence incidence.
Main Results:
- The overall recurrence rate of rLDH after minimally invasive discectomy was 12.13%.
- Patients with recurrent LDH showed a higher prevalence of Modic endplate changes and a decreased prevalence of no Modic changes.
- An increased prevalence of subligamentous herniations and a decreased prevalence of transligamentous herniations were observed in the recurrence group.
Conclusions:
- Minimally invasive discectomy has comparable recurrence rates to open microdiscectomy for LDH.
- Modic endplate changes are a significant risk factor for recurrent lumbar disc herniation.
- Subligamentous herniation subtype may be associated with an increased risk of recurrence, though further investigation is warranted.
Related Concept Videos
Herniated Intervertebral Disc l: Introduction
45
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
45
Degenerative Disc Disease I: Introduction
29
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
29
Degenerative Disc Disease ll: Pathophysiology
36
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
36

