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Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1

Jennifer Jelk1, Ningguo Gao, Mauro Serricchio

  • 1Department of Biochemistry, Weill Cornell Medical College, New York, New York 10065, USA.

The Journal of Biological Chemistry
|May 31, 2013
PubMed
Summary

Rft1 protein is not an M5-DLO flippase but may act as a chaperone for mature dolichol-linked oligosaccharide (mDLO) synthesis. This finding clarifies Rft1

Keywords:
Endoplasmic Reticulum (ER)FlippaseGlycobiologyGlycoprotein BiosynthesisLipid SynthesisMembrane ProteinsTrypanosoma brucei

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