[The immune changes at the beginning of pregnancy]

The authors investigated cellular and humoral immunity as well as the amount of circulating immune complexes (CIC) in 84 women, 52 of whom were healthy nonpregnant and 32 with normal pregnancy during the first trimester. Considerable changes were established in the immune status-depression of cellular immunity in pregnant women, an increase of the amount of CIC in the same women, humoral immunity did not show synonymous changes a reduction of IgG content in pregnant women and an increase of IgA in the same group. The level of IgM was not altered. The possible causes for the discovered changes are discussed.