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Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Mapping connectivity in the developing brain.

Emily L Dennis¹, Paul M Thompson

¹Imaging Genetics Center, Laboratory of Neuro Imaging, UCLA School of Medicine, 635 Charles Young Drive South, Suite 225, Los Angeles, CA 90095-7334, USA.

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience

|June 1, 2013

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This review explores brain connectivity development in typical and neurodevelopmental disorders. It highlights insights into the human connectome, developmental trajectories, and future research directions.

Area of Science:

Neuroscience
Developmental Neuroscience
Brain Imaging

Background:

Research on structural and functional brain connectivity has advanced our understanding of human brain development.
Numerous methods exist to assess brain connectivity, each with unique strengths.
Developmental changes in brain connectivity are crucial for understanding typical and atypical development.

Purpose of the Study:

To review recent findings on the development of structural and functional brain connectivity.
To examine connectivity in typically developing individuals and those with neurodevelopmental disorders.
To discuss common themes and future directions in connectomics research.

Main Methods:

Review of existing literature on brain connectivity development.

Keywords:

22q11.2 DS ADHD Autism Brain connectivity DTI Development Fragile X HARDI Turner syndrome Williams syndrome rs-fMRI

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Focus on studies examining autism, Fragile X, 22q11.2 deletion syndrome, Williams syndrome, Turner syndrome, and ADHD.

Synthesis of findings related to developmental trajectories and common themes.

Main Results:

Significant progress has been made in understanding the developmental trajectory of the human connectome.
Insights gained into characteristic features of brain development and biological processes in developmental disorders.
Common themes identified include hemispheric specialization and sex differences.

Conclusions:

The study of brain connectivity offers valuable insights into typical and atypical brain development.
Future research directions include integrating imaging and genetics, and exploring structural-functional connectivity relationships.
Continued investigation into the developing connectome is essential for understanding neurodevelopmental disorders.