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Updated: May 10, 2026
06:53
Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Adenoid basal cell carcinoma and its mimics
Sujata Jetley1, Zeeba S Jairajpuri, Safia Rana
1Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
Indian Journal of Dermatology
|June 1, 2013
Summary
Basal cell carcinoma (BCC), a common skin cancer, presents with diverse morphologies. This case highlights an adenoid BCC, emphasizing the role of immunohistochemistry in accurate diagnosis.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Background:
- Basal cell carcinoma (BCC) is the most prevalent malignant skin neoplasm.
- The head and neck region accounts for approximately 80% of BCC occurrences.
- BCC displays a wide spectrum of histopathological variants, including adenoid, keratotic, and sebaceous types.
Purpose of the Study:
- To present a case of adenoid basal cell carcinoma.
- To underscore the diagnostic challenges posed by BCC's varied morphology.
- To illustrate the utility of immunohistochemistry in differentiating BCC from similar neoplasms.
Main Methods:
- Clinical case presentation.
- Histopathological examination of tumor tissue.
- Immunohistochemical analysis to aid in diagnosis.
Main Results:
- An unusual case of adenoid basal cell carcinoma was identified in a 55-year-old male patient.
- Histopathological features were consistent with adenoid BCC.
- Immunohistochemistry confirmed the diagnosis and differentiated it from other cutaneous tumors.
Conclusions:
- Adenoid BCC represents a distinct morphological variant of basal cell carcinoma.
- Accurate diagnosis relies on a combination of clinical, histopathological, and immunohistochemical findings.
- Distinguishing BCC from entities like adenoid cystic carcinoma is crucial for appropriate patient management.
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