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Updated: May 10, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
Published on: April 4, 2014
N,N'-[2,2'-(Phenyl-aza-nedi-yl)bis-(ethane-2,1-di-yl)]dipicolinamide
Gao-Nan Li1, Zhi-Gang Niu, Mei-Qi Huang
1College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, People's Republic of China.
Abstract:
The asymmetric unit of the title compound, C22H23N5O2, contains two independent mol-ecules with similar conformations; the terminal pyridine rings are oriented at dihedral angles of 23.99 (8) and 18.07 (8)° with respect to the central benzene ring in one mol-ecule and 28.99 (8) and 23.22 (8)° in the other. In the crystal, N-H⋯O and weak C-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional supra-molecular structure. Weak inter-molecular C-H⋯π inter-actions are also observed in the crystal.
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