Related Experiment Video
Updated: May 10, 2026
07:30
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
Transoral laser microsurgery for early glottic cancer
Lisha McClelland1, Esmond Carr, Tawakir Kamani
1Royal Derby Hospital, Uttoxeter Road, Derby DE22 3NE, UK.
ISRN Otolaryngology
|June 1, 2013
Summary
Transoral laser-assisted microsurgery (TLM) effectively treats early glottic cancer, offering good tumor control and voice preservation. This technique shows promising results for local control and minimal impact on swallowing function in patients.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Oncology
Background:
- Early glottic carcinoma requires effective treatment for tumor control and functional preservation.
- Transoral laser-assisted microsurgery (TLM) is an endoscopic approach for laryngeal tumors.
Purpose of the Study:
- To evaluate the outcomes of TLM in early glottic cancer.
- Assess local and distant tumor control, voice quality, and swallowing function post-TLM.
Main Methods:
- Retrospective review of patients with early glottic tumors (Tis-T2) treated with TLM.
- Five-year follow-up assessing cancer-free survival, laryngectomy-free survival, and mortality.
- Evaluation of speech and swallowing function.
Main Results:
- High 5-year local control rates: 89% for T1 and 56% for T2 glottic tumors.
- Low laryngectomy rate (4.5%) and disease-specific mortality (4.5%).
- Good functional outcomes: 40% normal voice, 45% mild/moderate voice change, and no treatment-related swallowing difficulties.
Conclusions:
- Transoral Endoscopic CO2 laser microsurgery is a viable and effective treatment for early glottic tumors.
- TLM offers favorable oncological control with preservation of voice and swallowing functions.
