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Updated: May 10, 2026

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
Published on: October 2, 2016
An evidence-based systematic review of kratom (Mitragyna speciosa) by the Natural Standard Research Collaboration
Catherine Ulbricht1, Dawn Costa, Julie Dao
1Natural Standard Research Collaboration, Somerville, MA, USA. ulbricht@naturalstandard.com
Abstract:
An evidence-based systematic review of kratom (Mitragyna speciosa) by the Natural Standard Research Collaboration consolidates the safety and efficacy data available in the scientific literature using a validated, reproducible grading rationale. This article includes written and statistical analysis of clinical trials, plus a compilation of expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

