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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Peer support and interpersonal psychotherapy groups experienced decreased prenatal depression, anxiety and cortisol
Tiffany Field1, Miguel Diego, Jeannette Delgado
1Touch Research Institute, University of Miami Medical School, Miami, FL 33101, USA. tfield@med.miami.edu
Abstract:
Forty-four prenatally depressed women were randomly assigned to peer support or interpersonal psychotherapy groups at 22 weeks gestation. The peer support group participated in a 20-minute group session once per week for 12 weeks, and the interpersonal psychotherapy group met for one hour per week for 12 weeks. Assessments were conducted before and after the sessions at 22 and 34 weeks gestation. Despite the peer support group having lower socioeconomic status and higher depression scores at the beginning of the treatment period and having shorter group sessions, both groups had lower summary depression (CES-D) scores and lower anxiety (STAI) scores by the end of the treatment period. In addition, cortisol levels decreased for both groups after the last day session, although the decrease was greater for the peer support group. The groups did not differ on neonatal outcomes including gestational age and birthweight. These data suggest that peer support group sessions may be a cost-effective form of treatment for prenatal depression.
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