Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Systemic Arteries01:11

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.
Anatomy of the Circulatory System02:03

Anatomy of the Circulatory System

The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.
Overview of Systemic and Pulmonary Circulation01:15

Overview of Systemic and Pulmonary Circulation

The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Veins of Upper Limbs01:17

Veins of Upper Limbs

The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pathophysiology, prevention, and management of coronary microvascular obstruction.

European heart journal·2026
Same author

Small Subset, Big Impact: Regulatory Function of γδ T Cells in Arteriogenesis.

Cells·2026
Same author

PD-1/PD-L1 Signaling in Non-ICI Myocarditis.

JACC. Basic to translational science·2026
Same author

Genetic background is associated with distinct patterns of proarrhythmogenic remodeling leading to atrial fibrillation in pigs with ischemic heart failure.

Basic research in cardiology·2026
Same author

Clonal Hematopoiesis in Cardiovascular Risk: Focus on Inflammatory Mechanisms.

Journal of clinical medicine·2026
Same author

Colchicine Alleviates Non-Atherosclerotic Vascular Aging by Targeting Endothelial Dysfunction and Inflammatory Status.

Journal of inflammation research·2026

Related Experiment Video

Updated: May 10, 2026

Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

Peripheral circulation.

M Harold Laughlin1, Michael J Davis, Niels H Secher

  • 1Department of Medical Pharmacology and Physiology, and the Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri, USA. laughlinm@missouri.edu

Comprehensive Physiology
|June 4, 2013
PubMed
Summary
This summary is machine-generated.

During exercise, blood flow (BF) redistribution supports active muscles and vital organs. Chronic exercise training modifies these circulatory responses and vascular control mechanisms.

More Related Videos

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
10:50

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging

Published on: June 29, 2013

Related Experiment Videos

Last Updated: May 10, 2026

Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
10:50

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging

Published on: June 29, 2013

Area of Science:

  • Exercise Physiology
  • Cardiovascular Physiology
  • Sports Medicine

Background:

  • During exercise, blood flow (BF) distribution shifts significantly to meet metabolic demands.
  • Skeletal, cardiac, and respiratory muscles receive the majority of cardiac output during maximal exercise.
  • BF to non-essential tissues like gastrointestinal and renal systems decreases, while brain BF changes modestly.

Purpose of the Study:

  • To review the peripheral circulation response to acute and chronic dynamic exercise in humans.
  • To explore the mechanisms controlling BF distribution across various vascular beds during exercise.
  • To compare systemic and pulmonary circulation responses to exercise and training.

Main Methods:

  • Literature review of studies on human peripheral circulation during dynamic exercise.
  • Analysis of BF regulation in different vascular beds (skeletal muscle, brain, skin, etc.).
  • Examination of how exercise training alters these circulatory responses and control mechanisms.

Main Results:

  • BF increases in skeletal, cardiac, and respiratory muscles with rising exercise intensity.
  • Skin BF increases if exercise duration elevates core body temperature.
  • Changes in BF distribution are driven by alterations in vascular conductance, as blood pressure remains relatively stable.

Conclusions:

  • Exercise-induced BF redistribution is crucial for oxygen delivery to active muscles and maintaining homeostasis.
  • Understanding these responses is key to comprehending the physiological adaptations to exercise.
  • Chronic exercise training significantly modifies vascular control mechanisms, impacting BF distribution.