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Related Concept Videos

Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Updated: May 10, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
07:10

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy

Published on: June 18, 2020

Transjugular liver biopsy.

George Behrens1, Hector Ferral

  • 1Section of Interventional Radiology, Department of Radiology and Nuclear Medicine, RUSH University Medical Center, Chicago, Illinois.

Seminars in Interventional Radiology
|June 5, 2013
PubMed
Summary
This summary is machine-generated.

Transjugular liver biopsy (TJLB) offers a safe and effective alternative to traditional liver biopsy, especially for patients with bleeding risks or ascites. This technique yields high-quality tissue samples comparable to percutaneous methods, with low complication rates.

Keywords:
image-guidedinterventionalliver biopsytransjugular

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Area of Science:

  • Hepatology
  • Interventional Radiology
  • Gastroenterology

Background:

  • Liver biopsy is the gold standard for diagnosing liver disorders.
  • Transjugular liver biopsy (TJLB) provides an alternative method for obtaining liver tissue.
  • Advancements have made TJLB specimen quality comparable to percutaneous biopsy.

Purpose of the Study:

  • To review the fundamental aspects of the transjugular liver biopsy (TJLB) procedure.
  • To detail the technique, indications, contraindications, results, and complications of TJLB.
  • To highlight TJLB as a viable option for specific patient populations.

Main Methods:

  • Review of the transjugular liver biopsy (TJLB) technique.
  • Analysis of indications and contraindications for TJLB.
  • Evaluation of reported success rates, sample quality, and complication profiles.

Main Results:

  • TJLB technical success rates range from 87% to 97%.
  • Sample fragmentation occurs in 14% to 25% of TJLB procedures.
  • Complication rates for TJLB are low, ranging from 1.3% to 6.5%.

Conclusions:

  • Transjugular liver biopsy (TJLB) is a safe and effective procedure for liver tissue acquisition.
  • TJLB is indicated for patients with coagulopathy, ascites, morbid obesity, and other specific conditions.
  • The quality of TJLB specimens is comparable to percutaneous biopsy, with a low complication rate.