Related Experiment Video
Updated: May 10, 2026

Colonization of Euprymna scolopes Squid by Vibrio fischeri
Published on: March 1, 2012
The role of scurvy in Scott's return from the South Pole
1Medical School, University of St Andrews, Scotland, UK. arb3@st-andrews.ac.uk
Abstract:
Scurvy, caused by lack of vitamin C, was a major problem for polar explorers. It may have contributed to the general ill-health of the members of Scott's polar party in 1912 but their deaths are more likely to have been caused by a combination of frostbite, malnutrition and hypothermia. Some have argued that Oates's war wound in particular suffered dehiscence caused by a lack of vitamin C, but there is little evidence to support this. At the time, many doctors in Britain overlooked the results of the experiments by Axel Holst and Theodor Frølich which showed the effects of nutritional deficiencies and continued to accept the view, championed by Sir Almroth Wright, that polar scurvy was due to ptomaine poisoning from tainted pemmican. Because of this, any advice given to Scott during his preparations would probably not have helped him minimise the effect of scurvy on the members of his party.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Vitamins
Colonisation of Pathogens
Clinical Applications of Epidermal Stem Cells
Healing II: Complications
Cirrhosis II: Pathophysiology

