Synthesis and biological evaluation of novel tamoxifen analogues

Michael S Christodoulou1, Nikolas Fokialakis, Daniele Passarella

  • 1Chemistry Laboratory, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece.

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Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...