Related Experiment Video
Updated: May 10, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
Published on: April 4, 2025
A highly sensitive resonance Rayleigh scattering method to discriminate a parallel-stranded G-quadruplex from DNA
Yan Shi1, Hong Qun Luo, Nian Bing Li
1Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Chemistry and Chemical Engineering, Southwest University, Chongqing, PR China.
Abstract:
The RRS intensities are significantly increased only when a parallel-stranded G-quadruplex is added to Mg(2+) solution owing to the formation of G-wires between them, but the others cannot. So, we constructed a new and highly sensitive RRS method to discriminate a parallel-stranded G-quadruplex from DNA with other topologies and structures.
Related Concept Videos
Maxam-Gilbert Sequencing
Challenges of the Maxam-Gilbert Method
The...
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
X-ray Diffraction of Biological Samples
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are scattered by the electron clouds around the sample atoms. The X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...

