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Updated: May 10, 2026

In vivo Measurement of Knee Extensor Muscle Function in Mice
Published on: March 4, 2021
Leg extension test, sEMG and vibratory stimuli to assess functional recovery following knee joint surgery
Calogero Foti1, Alessandro Laurini, Simone Tiberti
1Physical and Rehabilitation Medicine, Tor Vergata University, Rome, Italy.
Objective:
the purpose of this study was to introduce new procedure to determine the magnitude of functional recovery after knee surgery.
Design:
we compared the performance in the leg extension test and the response in the sEMG activity to vibration in the operated to the non-operated leg. Thirty-eight patients with knee operation and 14 healthy subjects participated in these experiments.
Results:
during leg extension test, the mechanical power of the operated leg showed a lower value (P<0.001) than the contralateral one, while no differences were noted in the sEMG activity. The sEMG activity during vibration treatment was higher in the operated compared to non-operated leg (P<0.001). It has been suggested that the reduced motility trigger functional adaptations that are exhibited via the vibration test.
Conclusions:
results of our study suggest that combination of vibration and sEMG recordings may detect the impairment as well as monitoring progress of the rehabilitation programs.
