Related Experiment Video

Updated: May 10, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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Published on: October 25, 2016

One is better than two: TCR pairing and GVHD

Benjamin G Vincent1, Jonathan S Serody

  • 1Department of Medicine and the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

Science Translational Medicine
|June 7, 2013
PubMed
Summary

Dual T cell receptors (TCRs) were more common in patients experiencing acute graft-versus-host disease (GVHD) after stem cell transplants. This finding suggests a potential link between dual TCRs and GVHD development.

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