Dual PI3K/mTOR inhibitors: does p53 modulate response?

Oleksandr Ekshyyan1, Arunkumar Anandharaj, Cherie-Ann O Nathan

  • 1Department of Otolaryngology/Head and Neck Surgery and Feist-Weiller Cancer Center, LSU Health Sciences Center, Shreveport, Louisiana 71130, USA.

Summary

Genetic alterations in head and neck squamous cell carcinomas impact treatment response. Evaluating these distinct changes helps identify patients who benefit from targeted therapies, improving outcomes and reducing side effects.

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