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Vitamin D deficiency in infants aged 1 to 6 months
You Jin Choi1, Moon Kyu Kim, Su Jin Jeong
1Department of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
Insights
Vitamin D deficiency is common in South Korean infants, affecting nearly half. Breastfeeding significantly increases deficiency risk, highlighting the need for supplementation in all infants.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Vitamin D is crucial for infant health, particularly bone development.
- Deficiency can lead to rickets and other health issues.
- Optimal vitamin D levels are essential for overall infant well-being.
Purpose of the Study:
- To assess vitamin D status in South Korean infants aged 1-6 months.
- To identify key risk factors associated with vitamin D deficiency.
- To inform public health strategies for infant nutrition.
Main Methods:
- Serum 25-hydroxyvitamin D (25[OH]D) levels were measured in 117 infants.
- Data on feeding patterns, sex, and other factors were collected.
- Statistical analysis identified correlations with vitamin D levels.
Main Results:
- Nearly half (48.7%) of infants exhibited vitamin D deficiency.
- Breastfed infants showed a very high deficiency rate (90.4%).
- Lower vitamin D levels were observed in breastfed and female infants.
Conclusions:
- Vitamin D deficiency is prevalent in South Korean infants.
- Breastfeeding is a critical risk factor for deficiency.
- Early vitamin D supplementation is recommended for all infants.
Purpose:
The aim of this study was to recognize the state of vitamin D among healthy infants aged 1 to 6 months in South Korea, and also to identify the risk factors affecting the level of vitamin D.
Methods:
A total of 117 infants were enrolled in this study for 12 months, from March 1, 2011 to February 29, 2012. Serum levels of 25-hydroxyvitamin D (25[OH]D), calcium, phosphorus, and alkaline phosphatase were measured and data including birth weight, body weight, sex, feeding pattern, delivery mode, siblings and maternal age and occupation were collected. Data was mainly analyzed with independent t-test model.
Results:
We determined that the prevalence of vitamin D deficiency (serum 25[OH]D<20 ng/mL [50 mmol/L]) was 48.7% in the population investigated. Particularly in breastfed infants, the prevalence of vitamin D deficiency was strikingly high (90.4%). The mean serum level of 25(OH)D in breastfed infants was lower than that of formula fed infants (9.35 ng/mL vs. 28.79 ng/mL). Also female infants showed lower mean serum level of 25(OH)D than male. Mean serum values of calcium and phosphorus had positive correlation with vitamin D state (P<0.001).
Conclusion:
Vitamin D deficiency was found to be very common in infants aged 1 to 6 months in South Korea, and breast feeding was the most critical risk factor of vitamin D deficiency. Therefore we suggest to start vitamin D supplementation in South Korea, as soon as possible, to all infants, including breastfed and female infants.
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