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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Linear IgA disease in an adult with unusual clinical features
Rajesh Verma1, Biju Vasudevan, Vijendran Pragasam
1Department of Dermatology, Command Hospital (Southern Command), Wanowrie, Pune, Maharashtra, India.
Abstract:
A 19-year-old male presented with complaints of fluid-filled lesions on the body of 2 weeks duration. On examination, he was found to have multiple tense bullae distributed on the flexures, face, and genitalia with associated oral ulcers and "cluster of jewels" sign. The diagnosis was confirmed by histopathology and direct immunofluorescence. There are very few reports of linear IgA earlier from India according to the literature available so far, that too from the Southern part of the country. The patient had bullous pemphigoid-like lesions typically seen in adults, but the distribution of lesions was akin to that of the "chronic bullous disease of childhood variant" found in children. This case has been reported for rarity in this region and also because the patient had atypical morphology and distribution of lesions.
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