Postinfectious Manifestation of Wilson's Disease in COVID-19 Presenting as Writer's Cramp: A Case Report
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Rajesh Verma1, K P Arjun Bal, Rajarshi Chakraborty
1Department of Neurology, King George's Medical College, Lucknow, Uttar Pradesh, India.
Abstract:
Wilson's disease (WD) is a neurometabolic disorder of copper metabolism with varied neurological presentations. COVID-19 has been associated with a multitude of multisystemic involvement, especially nervous system due to direct involvement, systemic inflammation, and immune-mediated phenomena. Movement disorders, however, represent a small domain of COVID-19 illness. A 23-year-old male developed behavioral changes, writer's cramp, and other neuropsychiatric symptoms following a COVID-19 infection, leading to a diagnosis of WD. Examination revealed Kayser-Fleischer rings and brain imaging abnormalities. Diagnosis was confirmed by low ceruloplasmin levels, elevated 24 h urine copper, and genetic testing. This case highlights the postinfectious manifestations of WD and its rare presentation as a writer's cramp.
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