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Updated: May 10, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Stress echocardiography and mitral valvular heart disease
Julien Magne1, Patrizio Lancellotti, Luc A Pierard
1Department of Cardiology, GIGA Cardiovascular Sciences, Heart Valve Clinic, University Hospital Sart Tilman, University of Liège, Liège 4000, Belgium.
Abstract:
The European Society of Cardiology's updated guidelines emphasize the usefulness of exercise stress echocardiography in patients with valvular heart disease. Exercise-induced changes in valve hemodynamics should be assessed in patients with mitral valve disease. In asymptomatic patients with moderate or severe mitral regurgitation without left ventricular dysfunction/dilatation, exercise stress echocardiography may identify a subset of patients with reduced cardiac event-free survival who are at a higher risk of developing symptoms. In patients with mitral stenosis who are asymptomatic, the development of symptoms during exercise is strongly related to the kinetics of the changes in the systolic pulmonary arterial pressure.
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