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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

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Related Experiment Video

Updated: May 10, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Vacation appendicitis.

Jay A Redan¹, Michael B Tempel, Shannon Harrison

¹Department of Surgery, Florida Hospital-Celebration Health, Celebration, FL, USA. Jay.Redan.MD@flhosp.org

JSLS : Journal of the Society of Laparoendoscopic Surgeons

|June 8, 2013

Summary

This summary is machine-generated.

Vacationers experience a significantly higher rate of ruptured appendicitis compared to local residents. This study highlights a potential health risk associated with travel, particularly for appendicitis.

Related Experiment Videos

Last Updated: May 10, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Area of Science:

Medical research
Gastroenterology
Public health

Background:

Vacation planning often overlooks potential health risks, such as illness.
Abdominal pain during vacation planning is frequently ignored, delaying medical attention.

Purpose of the Study:

To investigate the association between being on vacation and the incidence of ruptured appendicitis.
To compare ruptured appendicitis rates in vacationers versus local residents.

Main Methods:

A comparative study of ruptured appendicitis cases was conducted between January 2007 and December 2008.
Incidence rates were compared between Florida Hospital-Celebration Health (near Walt Disney World) and Florida Hospital-Orlando (further from the tourist area).

Main Results:

Florida Hospital-Celebration Health reported a 60.59% rate of ruptured appendicitis, compared to 20.42% at Florida Hospital-Orlando.
Of patients treated for appendicitis, 155 at Celebration Health were identified as vacationers, versus only 21 at Florida Hospital-Orlando.

Conclusions:

A higher incidence of ruptured appendicitis was observed in patients on vacation compared to the local community in the Orlando, Florida area.
While not a direct cause-and-effect relationship, the findings suggest a correlation between vacation status and ruptured appendicitis risk.