Clinical manifestations of Campylobacter concisus infection in children

Hans Linde Nielsen1, Jørgen Engberg, Tove Ejlertsen

  • 1From the Departments of *Infectious Diseases and †Clinical Microbiology, Aalborg University Hospital, Aalborg; and ‡Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark.

Insights

Campylobacter concisus infections in children present with milder acute gastroenteritis but prolonged diarrhea compared to Campylobacter jejuni/coli. Late gastrointestinal complaints are similar between infections.

Area of Science:

  • Pediatric Infectious Diseases
  • Microbiology
  • Gastroenterology

Background:

  • Limited clinical data exists on Campylobacter concisus infections in pediatric populations.
  • Understanding the clinical impact of C. concisus is crucial for pediatric gastroenteritis management.

Purpose of the Study:

  • To determine the clinical manifestations of Campylobacter concisus (C. concisus) gastroenteritis in children.
  • To compare the clinical features of C. concisus infections with Campylobacter jejuni/coli infections in pediatric patients.

Main Methods:

  • A 2-year prospective study identified children (<18 years) with C. concisus-positive stool samples.
  • Clinical data were collected via questionnaires and medical records.
  • Manifestations were compared between C. concisus and C. jejuni/coli patient groups.

Main Results:

  • 85 children had C. concisus and 109 had C. jejuni/coli infections.
  • C. concisus patients showed significantly lower rates of fever, chills, and bloody stools.
  • Prolonged diarrhea (>2 weeks) was more common in C. concisus cases (50% vs 25%).

Conclusions:

  • Campylobacter concisus gastroenteritis in children has a less severe acute phase but a more prolonged course than C. jejuni/coli.
  • Children with C. concisus experience similar long-term gastrointestinal issues as those with C. jejuni/coli.
Abstract

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