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Published on: December 17, 2014
Pneumoperitoneum induces morphological alterations in the rat testicle
Carina Teixeira Ribeiro1, Diogo Benchimol De Souza, Jorge Luiz Medeiros
1Postgraduate Program in Physiopathology and Surgical Sciences, Urogenital Research Unit, UERJ, Rio de Janeiro, Brazil.
Purpose:
To investigate the seminiferous tubule histological morphology after an 8 mmHg pneumoperitoneum in the rat model.
Methods:
Fourteen rats were divided into two groups: a Sham group submitted to anesthesia and a pneumoperitoneum (Pp) group submitted to abdominal insufflation at 8 mmHg during three hours, followed by desuflation. All rats were killed after six weeks, testicles were collected and evaluated for the tubule diameter, germinative epithelium height and Johnsen´s score. Means were compared by using the Student's-t-test.
Results:
The seminiferous tubule diameter was diminished by 11.3% in the group submitted to pneumoperitoneum (p<0.05). No significant difference was found among the groups when analyzing the epithelium height and Johnsen´s score.
Conclusion:
In the rat model, the seminiferous tubules present structural alterations when subjected to pneumoperitoneum of 8 mmHg during three hours.
