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Published on: November 4, 2010
Correlation between bursting pressure and breaking strength in colonic anastomosis
Leonardo de Castro Durães1, Eliana Ferreira Ribeiro Durães, Luiz Felipe de Campos Lobato
1Postgraduate Program in Medical Sciences, School of Medicine, UnB, Brasilia-DF, Brazil. leonardoduraes@yahoo.com.br
Purpose:
To investigate the correlation between bursting pressure and breaking strength on the 7th postoperative day following left colonic anastomosis in rats.
Methods:
Seventy rats were randomly divided into seven groups of ten animals each. All of the animals underwent segmental resection of the left colon and end-to-end anastomosis. The animals in groups I to VI underwent surgical laparoscopies with pneumoperitoneums using carbon dioxide or helium at pressures of 5, 12 or 20 mmHg. In Group VII, open laparotomy was performed. The animals were reoperated on postoperative day 7 to measure the bursting pressure and the breaking strength of the anastomosis.
Results:
The anastomosis bursting pressure in 70 animals was 193.10±55.56 mmHg. There was no significant difference between the groups (p=0.786). The breaking strength of the anastomosis was 0.26±0.12 N. There was no significant difference between the groups (p=0.356). Pearson's correlation test showed a low correlation (r=0.231) lacking statistical significance (p=0.054).
Conclusion:
There was no correlation between the bursting pressure and breaking strength of left colonic anastomoses in rats on the 7th postoperative day.
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