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Related Concept Videos

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

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Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
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Hepatic pseudolymphoma: imaging-pathologic correlation with special reference to hemodynamic analysis.

Kotaro Yoshida1, Satoshi Kobayashi, Osamu Matsui

  • 1Department of Radiology, Kanazawa University School of Medicine, 13-1, Takara-Machi, Kanazawa, 920-8641, Japan, kotaroy@med.kanazawa-u.ac.jp.

Abdominal Imaging
|June 8, 2013
PubMed
Summary

Hepatic pseudolymphoma shows distinct radiological and hemodynamic features on CT, MRI, and angiography-assisted CT, aiding differentiation from liver tumors like hepatocellular carcinoma.

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Published on: August 18, 2016

Area of Science:

  • Radiology
  • Hepatology
  • Pathology

Background:

  • Hepatic pseudolymphoma is a rare benign liver condition.
  • Accurate radiological diagnosis is crucial for differentiating it from malignant tumors.

Purpose of the Study:

  • To correlate radiological findings with histopathology in hepatic pseudolymphoma.
  • To characterize hemodynamic features using advanced imaging techniques.

Main Methods:

  • Retrospective analysis of imaging (US, CT, MRI) in 10 hepatic pseudolymphomas.
  • Angiography-assisted CT (CTAP, CTHA) for hemodynamic assessment.
  • Comparison with histopathological findings.

Main Results:

  • Characteristic imaging features include hypoechoic/hypodense nodules with specific enhancement patterns.
  • CTAP revealed portal perfusion defects; CTHA showed irregular perinodular enhancement.
  • Histopathology confirmed lymphoid cell infiltration causing portal venule changes.

Conclusions:

  • Hepatic pseudolymphoma exhibits specific radiological and hemodynamic patterns.
  • These findings assist in differentiating it from hepatocellular carcinoma and other liver neoplasms.